*SET-U

English word origin

Etymology of VEXAS

Acronym of vacuoles, E1 enzyme, X chromosome, autoinflammatory, somatic, after the core features of the disorder. First discovered in October 2020, with the report from The New England Journal of Medicine and identified

1 source sectionExtended source reportWiktionary original ↗
In this entry · 1 source sections

The source etymologies

Wiktionary via Kaikki / Wiktextract

The source reports below are imported and unreviewed by *SET-U. Separate numbered origins and differing source variants are preserved; agreement within this extraction is not independent corroboration.

Unnumbered source etymology

Original entry ↗
noun

An autoimmune disease that causes inflammation in the body and mostly affects men.

Selected source glosses provide context, not a complete modern definition inventory

Acronym of vacuoles, E1 enzyme, X chromosome, autoinflammatory, somatic, after the core features of the disorder. First discovered in October 2020, with the report from The New England Journal of Medicine and identified by a multidisciplinary team of scientists (see quotations below).

Inspect preserved source fields

Raw extraction fields are retained for auditing. Their order does not establish ancestry.

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        "2": "vacuoles, E1 enzyme, X chromosome, autoinflammatory, somatic"
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      "expansion": "Acronym of vacuoles, E1 enzyme, X chromosome, autoinflammatory, somatic"
    }
  ],
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      "vacuole#English"
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      "X chromosome#English"
    ],
    [
      "autoinflammatory",
      "autoinflammatory#English"
    ],
    [
      "somatic",
      "somatic#English"
    ]
  ],
  "references": [],
  "descendants": [],
  "lexical": [
    {
      "pos": "noun",
      "glosses": [
        "An autoimmune disease that causes inflammation in the body and mostly affects men."
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Where this record stops

This page does not supply an independently verified sound-change sequence, first-use manuscript or complete family tree unless a cited analysis explicitly establishes one. Missing detail here is a limit of this record—not a claim that humanity knows nothing more.

An older meaning does not determine what a word must mean today. Follow the sources, preserve disagreements, and keep ancestry separate from interpretation.

Contribute located evidence for VEXAS →

Source and snapshot

Imported from Wiktionary contributors; extracted by Tatu Ylonen / Wiktextract / Kaikki.org. Selected fields are reformatted and grouped; wording, source identity and etymology sections are retained. CC-BY-SA-4.0 applies to the imported source material.

Dump: 2026-10-01 · Extracted: 2026-10-30. These are snapshot dates, not the word’s first attestation or the page’s revision date.

Source entry and bibliography ↗Wiktionary revision history ↗Acquisition and rights ledger
Machine-source provenance
Source SHA-256
5ff2c072f8099f2d2ce484bd6957bf179f046d2ad37bc36555edf8bb84cb5291
Import run
73216b9a9b78ed3830994bf853103716f5a4dc57099e371e9f8fdc468facca26
Permanent entry ID
w-VkVYQVM